sIgE to peanut components does not accurately predict the severity of allergy in subjects suspected of peanut allergy

Methods Peanut allergic adults (n=94) and children (n=100) with a suspected peanut allergy were included. sIgE levels were measured by ImmunoCAP (Uppsala, Sweden). In all subjects the adapted Mueller score was used with one additional category for no symptoms (0-5): 0; no symptoms/peanut tolerant, 1; oral allergy symptoms, 2; cutaneous/mucosal symptoms, 3; gastrointestinal symptoms, 4; respiratory symptoms, 5; cardiovascular symptoms. A severe reaction was defined as a Mueller score of 4 or 5. Univariate and multivariate logistic regression analysis was used to calculate odds ratio’s.